Bioinformatics

In partnership with Fios Genomics Ltd. we offer a wide range of bespoke data analysis solutions and bioinformatics for a variety of application areas (e.g. gene expression and methylation analysis). Services range from data QC and basic statistics to advanced approaches such as network and pathway based analysis, clustering techniques and data mining/integration methods to produce a comprehensive picture of the underlying biology of your experiment.

Fios Genomics is a provider of an extensive range of bioinformatics data analysis services to pharma, CROs and academia for drug discovery & development and applied research across all species. Using proprietary computer solutions enables Fios to analyse large datasets in parallel saving processing time and avoiding the complications that can arise when analysing data in batches.

Fios are specialists in the analysis of high dimensional, multi-variant datasets and in recognising patterns and trends associated with a trait, disease or drug response from genomic, transcriptomic or proteomic data.

Specific microarray associated services include:

• Analysis of gene expression profiling data for all the major commercial microarray providers (Affymetrix, Illumina, Agilent, Roche Nimblegen) as well custom microarray platforms and exon arrays, offering computationally innovative solutions to help you overcome challenges in genomic microarray analysis.
• Range of epigenetic analyses including DNA methylation profiling and ChIP-on-chip analysis to help identify the factors regulating expression of genes or biomarkers implicated in disease or drug response.
• Full range of SNP genotyping services which can include SNP filtering, linkage disequilibrium, haplotype analysis, genotype calls, genome-wide association studies (GWAS) and copy number variation (CNV) analysis.
• RNAi and miRNA analysis which include differential gene expression, target selection and siRNA off-target analysis.